What is mesothelioma ,and any different types? Question 1 2 3

What is mesothelioma?
 
Malignant mesothelioma is a rare form of cancer that is found in the lining of the chest and lung (the pleura), the abdomen (the peritoneum), or the saclike space around the heart (the pericardium). Although it is rare, mesothelioma is a very serious disease that is often at an advanced stage when the diagnosis is made.

In the United States an estimated 2000 to 3000 new cases of mesothelioma are diagnosed each year.

Approximately three fourths of these cases start in the chest cavity and are called pleural mesotheliomas. Another 10% to 20% begin in the abdomen and are called peritoneal mesotheliomas. Lastly, those that start in the lining around the heart are called pericardial mesotheliomas, but these are extremely rare.

Pleura (PLOOR-a)  A thin layer of tissue covering the lungs and lining the interior wall of the chest cavity. It protects and cushions the lungs. This tissue secretes a small amount of fluid that acts as a lubricant, allowing the lungs to move smoothly in the chest cavity while breathing.
Peritoneum (PAIRih-toe-NEE-um)  The tissue that lines the abdominal wall and covers most of the organs in the abdomen which is composed of mesothelial cells and is the target organ for abdominal mesothelioma.
Pericardium  The heart sac that covers the heart 


2. Are there different types of mesothelioma?

Mesothelioma is divided into three main types, based on what the cancer cells look like under the microscope. The most frequent type is epithelioid. About 50% to 70% of mesotheliomas are of this type. It usually has the best prognosis or outlook of the three. The second type is called the sarcomatoid, which makes up about 7% to 20% of mesotheliomas.

It has a very unpredictable pattern or nature. The last type, called mixed or biphasic, is a combination of the first two types and makes up about 20% to 35% of mesotheliomas. Although there are different types of mesothelioma, the treatment options, at this time, are essentially the same for all types.
Epithelial (ep-ihTHEE-lee-ul) Refers to the cells that line the internal and external surfaces of the body and the term used to describe the appearance of the cells under the microsope for the most common type of mesothelioma.
Sarcomatoid  The least common variant of mesothelioma which has the appearance under the microscope of spindly cells which look like supportive or connective tissue  
Biphasic  A mesothelioma which has both epithelial and sarcomatoid elements. Also called a mixed mesothelioma.  


3. What is the pleura?

The pleura is a sheetlike lining formed by rectangular cells called mesothelial cells, and is usually not more than a few layers thick. There are two pleuras in the chest; the parietal pleura lines the inside of the chest wall like wallpaper, covering not only the inside of the ribs but also the diaphragm (the muscle in between the chest and abdominal cavities that moves with breathing) and pericardium. The normal parietal pleura is no more than 2 to 3 mm thick, where the normal visceral pleura is fused to the lung and is about 1 mm thick.

The visceral pleura is a separate pleura that covers the lung and is much more difficult to remove without harming the lung. The pleura filters fluid back and forth from the chest to the circulation in the normal human, but it is expendable if it becomes diseased. If the pleura becomes diseased, it is not as effective in eliminating fluid from the chest, and fluid accumulation (pleural effusion) can occur. 
Parietal pleura  The lining on the inside of the chest wall which is composed of mesothelial cells and is the target organ for asbestos induced mesothelioma.

Visceral pleura  The mesothelial living on the surface of the lung which can also be a target organ for mesothelioma.  



What is mesothelioma ,and any different types? Question 1 2 3 What is mesothelioma ,and any different types? Question 1 2 3 Reviewed by Ari on 6:00 AM Rating: 5

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